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Dual Processing Model of Visual Information - Hitoshi Sasaki - Bog - Nova Science Publishers Inc - Plusbog.dk

Teleosts - - Bog - Nova Science Publishers Inc - Plusbog.dk

Teleosts - - Bog - Nova Science Publishers Inc - Plusbog.dk

The authors begin this compilation by analyzing catalase and peroxidase enzymes in different Black Sea teleosts related to their taxonomic, physiological and ecological position and evaluation of the anthropogenic impact on these antioxidant enzymes in fish tissues. The complex of specific phylogenic, physiological and ecological features of fish species may modify their antioxidant status, and it is important to understand for the development of monitoring programs. Next, the ratio of constitutive and reparative neurogenesis in the pallium of the juvenile masu salmon, Oncorhynchus masou, is analyzed. Since salmonid juveniles are characterized by a high level of constitutive neurogenesis, the authors investigated proliferative activity and neurodifferentiation in the dorsal pallial area of the masu salmon juvenile. The study has allowed for indentification of the superficially located periventricular proliferative zone, which corresponds to the pallial periventricular zone of other fish species. The objective of the final chapter was to study proliferation processes and the role of radial glia and neural stem cells in the event of injurious action on cerebellum of masu salmon juveniles. Using the immunoperoxidase staining of the glial fibrillary acidic protein, doublecortine and proliferating cells nuclear antigen, processes of proliferation and gliogenesis after mechanical trauma of cerebellum of masu salmon juveniles were studied.

DKK 820.00
1

Attention-Deficit Hyperactivity Disorder - - Bog - Nova Science Publishers Inc - Plusbog.dk

An In Depth Look at Hungary - - Bog - Nova Science Publishers Inc - Plusbog.dk

A Comprehensive Review of Significant Geological Eras - - Bog - Nova Science Publishers Inc - Plusbog.dk

Epidermolysis Bullosa (EB) - - Bog - Nova Science Publishers Inc - Plusbog.dk

Fragile X Syndrome - - Bog - Nova Science Publishers Inc - Plusbog.dk

Fragile X Syndrome - - Bog - Nova Science Publishers Inc - Plusbog.dk

Fragile X syndrome is an inherited disease caused by an excessive length of the FMR protein due to mutations in the FMR1 gene located on the X chromosome. It is commonly described as one of the most common genetic diseases with autism-like behaviours and related developmental disabilities. Beside intellectual delays, behavioural problems, and communication difficulties, mood disorders usually occur. Diagnosis is based on laboratory tests and DNA results. Phenotypes including long and narrow face, large ears, hyper-arched palate, flat feet, ataxia, seizures, anxiety, aggression, and hand-related stereotypic behaviours are frequently observed. Although there is no specific cure, early interventions are highly encouraging, promising, and recommended. Pharmacological treatments may be combined with behavioural and/or cognitive behavioural interventions. Recently, assistive technology-based programs have been implemented. This volume includes seven chapters and addresses the newest advances in the diagnosis and treatment of individuals with Fragile X syndrome. Chapter One encompasses the molecular features and pathological bases of the disease. A comprehensive literature overview was conducted. The role of the FMR protein was emphasized although few studies evaluated its function. Chapter Two deals with the neuropsychiatric symptoms related to the syndrome. A complete conceptual framework was exhaustively detailed. Chapter Three emphasizes the role of pharmacotherapy in the treatment of Fragile X syndrome. A further literature review was carried out. Clinical relevance was outlined. Chapter Four provides the reader with a conceptual analysis. Besides molecular features, brain development was described. Challenging behaviours were included and the importance of the early combined intervention was critically discussed. Chapters Five, Six, and Seven detailed three case reports on the effectiveness and the suitability of assistive technology-based interventions. Specifically, Chapter Five argued for microswitch-cluster technology focused on pursuing the dual simultaneous goal of promoting an adaptive response (i.e., object manipulation) and reducing a challenging behaviour (i.e., hand mouthing). Chapter Six describes a combined microswitch and VOCA program useful to ensure the participant has the choice between independent access to positive stimulation and asking for social interaction. Finally, Chapter Seven includes choice opportunities through an assistive technology-mediated program involving a boy with Fragile X in a functional task. Targeted readers (i.e., caregivers, clinicians, speech therapists, professionals, psychologists, neurologists, parents of children with Fragile X syndrome, teachers) may find interesting and stimulating tips and insights for daily use in clinical research and practice, with the dual objective of diagnosis and treatment.

DKK 718.00
1

Ethnic Differences - - Bog - Nova Science Publishers Inc - Plusbog.dk

Calcium Signaling and Nervous System - Victor V. Chaban - Bog - Nova Science Publishers Inc - Plusbog.dk

Calcium Signaling and Nervous System - Victor V. Chaban - Bog - Nova Science Publishers Inc - Plusbog.dk

This book provides comprehensive insights into emerging trends on calcium signaling in the nervous system from triggering signal transduction neuronal pathways to regulation of brain functions. Calcium signaling is one of the major coupling mechanism linking external stimuli with intracellular processes. Normal calcium signaling is important for functioning of all cells particularly neurons coupled to control mechanisms of the body inducing intra- and intercellular signaling and triggering biochemical cascade to control metabolism, gene expression, cell differentiation and apoptosis. The author, Dr. Victor V. Chaban is Professor of Medicine with dual appointment at Charles R. Drew University of Medicine and Science (CDU) and University of California Los Angeles (UCLA). Dr. Chaban completed his post-doctoral training in Neuroscience at UCLA and graduate studies in Clinical Research at CDU. He serves on National Institute of Health and several international study sections and holds U.S. Patents. Prof. Chaban is established expert, who contributed significantly to a better understanding of neuroplasticity and neurodegeneration associated with changes in calcium signaling. Calcium Signaling and Nervous System: Overview and Directions for Research gives an up to date account of changes in intracellular Ca2+ associated with primary afferents sensitization, neuronal and glial reorganization, neuroprotection and neurodegeneration. This book is recommended to scientists, healthcare providers, students and patients.

DKK 624.00
1

Unsaturated Soils - - Bog - Nova Science Publishers Inc - Plusbog.dk

Unsaturated Soils - - Bog - Nova Science Publishers Inc - Plusbog.dk

This compilation opens with an exploration of the vadose, or unsaturated zone, which is of utmost importance as the nexus between surface water and groundwater. It is the link between what happens on the surface and what happens below, inside the aquifers. As such, understanding this underground natural environment is essential for the sustainable development of society. Due to the complexities involved in considering the hysteretic response of the Soil Water Characteristic Curve and its dependency on volume changes, these two features are often ignored in numerical studies of unsaturated soils. To facilitate their use in numerical modeling, a model for the Soil Water Characteristic Curve equation based on the bounding surface concept is proposed. The authors go on to focus on the temperature distribution and water migration in unsaturated soil, which is of significant importance because these factors are related to the thermal-physical properties of soil. The changes in these properties may cause disastrous engineering problems such as the cracking of pavement, damage of structure foundation and fracture of pipelines. Lastly, the book addresses the measurement and expression of the mass chemical potential in the presence of superficial layers induced by a complex structure. By definition, the mass chemical potential of a constituent in a soil represents the variation of the internal energy of the medium when a unit mass of the constituent is transferred to a reference state with the entropy, volume and mass of the other constituents remaining constant.

DKK 718.00
1

The Traditional Sakkiya Practice - - Bog - Nova Science Publishers Inc - Plusbog.dk

The Traditional Sakkiya Practice - - Bog - Nova Science Publishers Inc - Plusbog.dk

Sakkiya is a Hausa word, which has its origin from the Hausa culture, and it means the act of using hot pointed metallic tip to puncture bodily swelling with the aim of achieving a curative effect. The Hausa culture is one of the three most popular cultures in Nigeria. The Hausas are predominantly located in the northwestern geopolitical zone of Nigeria, predominantly working as farmers. The majority of the Hausa people practice the Islamic religion. Encounters from the medical setting with cases of complications arising from failure of Sakkiya treatment, where some patients did not survive this treatment made investigation into this form of alternative medicine a paramount issue. In order to fill the void of information and literature on Sakkiya treatment, the authors embarked on a literature search and field studies resulting in this book. The authors found a lack of historical evidence concerning the old traditional Sakkiya practice, and therefore urge archaeologists, anthropologists, sociologists and historians to investigate into the historical evolution of Sakkiya practice in northern Nigeria.Kehinde Kanmodi, BDS, ACIPM, AISQEM is a dental surgeon, lecturer, multidisciplinary researcher, and manager affiliated with Cephas Health Research Initiative Inc, Ibadan (head office), Community Health Officers Training Programme, Usmanu Danfodiyo University Teaching Hospital, Sokoto, National Teachers Institute, Department of Political Science of the National Open University of Nigeria, Abuja, Nigerian Institute of Management, Abuja, Chartered Institute of Project Management, Lagos, and Dental Clinic, Kebbi Medical Centre, Kalgo, Nigeria.Joav Merrick, MD, MMedSci, DMSc, born and educated in Denmark is professor of pediatrics, child health and human development affiliated with the Division of Pediatrics, Hadassah Hebrew University Medical Center, Mt Scopus Campus, Jerusalem, Israel, Kentucky Childrens Hospital, University of Kentucky, Lexington, United States and professor of public health at the Center for Healthy Development, School of Public Health, Georgia State University, Atlanta, United States, the former medical director of the Division for Intellectual and Developmental Disabilities, Ministry of Social Affairs and Social Services, Jerusalem and the founder and director of the National Institute of Child Health and Human Development in Israel.

DKK 624.00
1

Understanding Children with Cerebral Palsy - - Bog - Nova Science Publishers Inc - Plusbog.dk

Understanding Children with Cerebral Palsy - - Bog - Nova Science Publishers Inc - Plusbog.dk

Cerebral Palsy (CP) represents one of the most frequent neurological disorder in the infancy and in the childhood. It includes brain injuries or developmental defects. According to the World Health Organization, it is a main problem of public health. It may include communication, intellectual, and motor disabilities with negative consequences on children inclusion in daily life and caregivers burden. Rehabilitative interventions are primarily focused on promoting self-determination and independence of individuals with CP. Postural control, gait, and motor skills are usually embedded. Additionally, one may envisage request and choice programs aimed at enhancing the child's awareness of his/her own behavior. The volume summarizes some illustrative evidence-based contributions to emphasize the effectiveness and the suitability of the adopted programs. Beside stability of upper limbs and motor performance of children with CP (chapter one), the therapeutic effects of a horse riding simulator which was compared to a traditional physiotherapy on the sitting position of children with spastic CP (chapter two), the evaluation of stability in children with different form of CP was assessed through a rehabilitative platform was implemented (chapter three). The aforementioned experimental examinations presented between-groups investigations. Furthermore, four case-report studies were included. Assistive technology-based setups were used to promote an active role, constructive engagement, and positive participation of the enrolled children with CP and intellectual disabilities. The beneficial outcomes on their quality of life were considered. Chapter four describes a microswitch-based program to enhance ambulation responses of a child with CP. Chapter five provides a detailed illustration of such program to support locomotion fluency. Chapter six illustrates a cluster-technology aimed at pursuing the dual goal of fostering an adaptive response and reducing a challenging behavior. Chapter seven refers to a computerized system focused on enabling a child with CP and intellectual delays with academic performance and communication opportunities. Whenever available, the effects on indices of happiness and/or positive participation were analyzed. Social validation procedures involving external raters were conducted. Practical features of the retained treatments were privileged. Clinical, educational, psychological, and rehabilitative implications of the findings were systematically and critically discussed. Caregivers, educators, families of children with CP, practitioners, psychologists, speech and occupational therapists, medicine or psychology students, and teachers may find some useful insights for both research and practice in daily life settings.

DKK 624.00
1

Joint Imaging Applications in General Neurodegenerative Disease - Yongxia Zhou - Bog - Nova Science Publishers Inc - Plusbog.dk

Joint Imaging Applications in General Neurodegenerative Disease - Yongxia Zhou - Bog - Nova Science Publishers Inc - Plusbog.dk

Multiple advanced neuroimaging applications in various neurodegenerative diseases including Parkinson's disease (PD), frontotemporal dementia (FTD), vascular dementia (VaD) and autism spectrum disorder (ASD) are covered in this book. Relatively novel techniques such as integrated PET/MRI and independent component analysis (ICA)-based dual regression (DR) methods were developed to capture multi-level molecular/functional and structural/microstructural as well as high-order inter-network coordination abnormalities. For instance, both PET dopamine transporter and striatal binding ratio reductions in the caudate and putamen were found in PD, consistent with the diffusion tensor imaging (DTI) fractional anisotropy (FA) reduction and fMRI voxel-mirrored homotopic correlation (VMHC) in the substantia nigra (swallow tail sign signature of PD). Furthermore, dopamine storage and pathway labeled with the vesicular monoamine transporter tracer identified decreased densities in the bilateral mesial temporal cortex, caudate, orbitofrontal cortex, left frontal and occipital cortices, consistent with the morphological atrophy, functional connectivity and conductivity deficits in PD. Similarly in FTD patients, the advanced MRI methods such as ICA-DR, VMHC, voxel-based morphometry (VBM) as well as PET tracer for amyloid accumulation and FDG glucose uptake identified typical brain atrophy, structural dis-connectivity, glucose hypometabolism, higher neuropathological burden, lower interhemispheric correlation as well as disrupted intra- and inter-network modulation in the orbitofrontal and anterior temporal cortices together with insular and frontoparietal networks, with the cerebellum and dorsolateral attentional network as typical compensations. Functional and structural abnormalities had further been elucidated in the VaD dependent participants and autistic children. For instance, both lower FA and VMHC, brain atrophy and functional connectivity deficits, demyelination, axonal degeneration and white matter integrity damage in several white matter tracts were present in the dependent compared to independent participants in VaD data cohort. Increased neuronal activity with higher global fractional amplitude of low frequency fluctuation (fALFF) in the conventional and slow-wave sub-band was confirmed with less efficiency of systematic integration in VaD dependent group. Moreover, in ASD compared to controls, regional gray matter volume and cortical thickness in all four brain lobes increased, whereas white matter volume were decreased in addition to the lower temporal, visual and superior frontal but higher inferior and dorsolateral prefrontal cortical functional connectivities exhibited in ASD. The differences in each type of disease could also be revealed with the same imaging method based on either unique region or distinct brain circuit inter-connection, using VMHC, ICA-DR, DTI, VBM, fALFF and graph-theory based small-worldness analysis. In this book, we have developed and generalized conventional and advanced imaging methodologies to several common neurodegenerative diseases. For instance, we have identified the unique imaging signature for each disease type and the underlying neuropathological mechanism connections with conductivity, structural and microstructural connectivity, intra- and inter-network correlation, systematic integration and efficiency analyses. Our objective, comprehensive and confirmative results indicated great potential in utilizing these quantifications for accurate disease classification and staging. With solid imaging evidence, thorough analysis and generalized applications, this book should capture the interests of readers in the broad fields of brain science, disease diagnosis and effective treatment.

DKK 718.00
1