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Understanding Heat Conduction - - Bog - Nova Science Publishers Inc - Plusbog.dk

Monte Carlo Methods - - Bog - Nova Science Publishers Inc - Plusbog.dk

Benzothiazole - - Bog - Nova Science Publishers Inc - Plusbog.dk

An Introduction to Electronic Structure Theory - - Bog - Nova Science Publishers Inc - Plusbog.dk

Pediatric Critical Care - - Bog - Nova Science Publishers Inc - Plusbog.dk

Pediatric Critical Care - - Bog - Nova Science Publishers Inc - Plusbog.dk

This practical handbook of paediatric critical care is written for all clinicians who care for children with acute illness. Specifically, chapters are written to provide helpful insights to all levels of paediatric providers including PICU nurses, Advanced Practice Nurses based in the PICU, medical students, paediatric residents, residents from other disciplines who rotate through PICU, hospitalists who may need to stabilize children prior to transfer to the PICU, and emergency physicians who may want to refer patients to the PICU. In addition to covering PICU-specific topics such as mechanical ventilation and procedural sedation, this handbook also includes guidance in the initial resuscitation, management and stabilisation of critically ill children. Management of life-threatening situations that are specifically included in this book include respiratory failure, cardiovascular failure, electrolyte derangements, diabetic ketoacidosis, burn injuries, status epilepticus, status asthmaticus, toxic ingestions, and sepsis, among many others. This easy-to-read handbook covers basic and fundamental concepts of paediatric critical care medicine and makes for easy reading when on call, at the bedside, or when evaluating a child who may need critical care services. At the same time, Pediatric Critical Care: A Primer for All Clinicians provides a quick and practical reference with high-yield information for the clinician who finds themselves in an emergency situation in need of immediate guidance for stabilization and management. We hope that you enjoy this compendium and most of all our intent is that you will find it useful and practical in the everyday care that is provided to critically ill neonates, infants, children and adolescents with the wide array of critical illnesses that you encounter every single day.

DKK 671.00
1

Is Aging a Disease? - Michael A. Singer - Bog - Nova Science Publishers Inc - Plusbog.dk

Is Aging a Disease? - Michael A. Singer - Bog - Nova Science Publishers Inc - Plusbog.dk

Each species has its own characteristic aging trajectory coded by a species-specific developmental program. This developmental program is triggered at the time of fertilization, hence aging begins at conception. Within a species there are considerable variations in the aging phenotype between individuals due to the plasticity of the developmental process and its inherent stochasticity. The evolution of a species is due to genetic changes in its underlying developmental program and when enough genetic changes have accumulated a new species emerges with its own characteristic aging phenotype. Therefore, speciation and aging are linked processes. Over the evolutionary course of the human lineage, culture has been an important driver of evolutionary change. Culture is not restricted to the human lineage but only humans have evolved cumulative culture; the transmission of modified cultural practices across generations. Early cultural innovations such as toolmaking, agriculture and dairy farming had a utilitarian function. However, over the past 100 to 150 years, there has been a significant change in the pace and nature of cultural innovations. Although many cultural innovations still have a utilitarian function, a new category of cultural innovations has emerged that have "entertainment" functions in the domains of social communication and information transfer. In addition, cultural practices by the tobacco, food and technological industries have been used to modify population behaviors, physiology and beliefs. Over the past 50 to 75 years, there has emerged so called chronic non-infectious diseases, which occurrence parallels the development of these new cultural innovations and practices. In addition, culture has now become the primary driver of human evolution. In answer to the question posed by the title of this book, aging is not a disease and diseases are cultural constructs used to define variants in the aging process.

DKK 718.00
1

Human Serum Albumin - - Bog - Nova Science Publishers Inc - Plusbog.dk

Human Serum Albumin - - Bog - Nova Science Publishers Inc - Plusbog.dk

Human serum albumin is found in the intravascular and extracellular space and is the main protein of human blood plasma. Human serum albumin binds water, cations (such as Ca2+, Na+, K+), fatty acids, hormones, bilirubin, thyroxin (T4) and pharmaceuticals. Structurally, the serum albumins are similar, each domain containing five or six internal disulfide bonds. In the opening chapter of Human Serum Albumin: Structure, Binding and Activity the authors review, the structure, content and binding of HSA. Then, the role of albumin in free radical trapping activities and as an oxyradical scavenger is described. A discussion of recent advances in the use of the antioxidant properties of human serum albumin to make drugs detectable in vivo is also presented. Human serum albumin has one tryptophan residue and shows a characteristic fluorescence of around 350 nm under ultraviolet irradiation. Because tryptophan is easily oxidized by reactive oxygen species and/or photoexcited molecules through electron transfer (leading to fluorescence diminishment) a fluorometry of this tryptophan residue is a useful tool to evaluate oxidation. In light of these characteristics, the authors examine the photosensitizing activity of organic photosensitizers, including porphyrins and phenothiazine dyes. The use of magnetic resonance imaging and spectroscopy for the determination of human serum albumin structure, drug binding and in vivo activity is explored, in addition to drug modifications using human serum albumin. Following this, this compilation studies the major approaches for the characterization of human serum albumin as a fluorinated drug delivery agent and fluorinated albumin influence on drug binding. Synthesis and characterization of fluorinated conjugates of albumin and adsorbed human serum albumin on surfaces containing CF3 are also discussed. The concluding study investigates possible similarities and differences in albumin concentration and the presence of tyrosine in urine from a population of healthy and microalbuminuria dependent women. The assessment of subtle changes in albumin concentration, the primary macromolecular component of urine, is critical for the diagnosis of early stage albuminuria, one of the major complications in nephropathy.

DKK 624.00
1

An Interdisciplinary Approach towards Academic Education on Sustainable Building Design - - Bog - Nova Science Publishers Inc - Plusbog.dk

An Interdisciplinary Approach towards Academic Education on Sustainable Building Design - - Bog - Nova Science Publishers Inc - Plusbog.dk

The built environment is witnessing a worldwide concern followed by intensive consideration of its environmental impacts on the one hand and influence on public health and wellbeing on the other. Respecting both priorities mentioned above, the trends in current design tend to be in line with multiple dimensions of sustainability. Next to its occurrence in scientific research and practice, the topic of sustainable design is ever more emerging within the courses at universities, whereby the educational approaches can be beneficial if interrelated to different scientific or expert disciplines. As universities are recognized as complex organizations inevitably evolving over a long period of time period and responding to changes in society and environment, attempts to improve the efficiency of academic teaching have been intensively introduced also in the study programs of the University of Maribor, Faculty of Civil Engineering, Transportation Engineering and Architecture (UM FGPA) through implementation of various activities related to development of innovative approaches towards education on sustainable design of built environment. The publication presents the interdisciplinary approach to the academic education on sustainable building design through integration of different activities. In addition to basic educational courses, the transfer of latest research findings, implementation of practical student workshops, development projects and various activities aiming at integration of different knowledge transfers makes the level of academic teaching more active and efficient. The book consists of six chapters. The first chapter describes the general aspect of the integrative approach to education on sustainable built environment through the experience of the interdisciplinary course. Chapter 2 introduces a comprehensive set of urban design criteria for creating residential neighbourhoods and emphasizes the role of high-quality open space and green areas, which significantly contributes to liveability. Chapter 3 deals with sustainable transport in connection with the living environment, and emphasises the interdisciplinary approach. Chapter 4 presents the inclusion of energy-efficient building design with the integrated use of new digital technologies, such as building information and energy modelling. Chapter 5 describes the main types of timber structural systems and presents a sustainable design perspective of contemporary prefabricated timber-glass buildings with further development of multi-storey prefabricated timber buildings with enlarged glazing areas. The last chapter is prepared as a graphic summary of interdisciplinary workshop projects which demonstrate the complexity of design and the respect for diverse interdisciplinary principles of sustainable planning.

DKK 718.00
1

Modeling of the Soil-Structure Interaction - - Bog - Nova Science Publishers Inc - Plusbog.dk

Modeling of the Soil-Structure Interaction - - Bog - Nova Science Publishers Inc - Plusbog.dk

This edited book provides discussion and presents results related to some "hot topics," all dealing with the soil-structure interaction. The book can be of interest to both scientists involved in academic studies of the problems addressed and for practitioners engaged in high-level design. Chapter I reports the investigation of non-stationary wave propagation in continuously inhomogeneous cylindrical elements (such as pipelines). New results obtained by numerical analysis of non-stationary wave propagation are presented. The cases studied comprise simulations of the propagations of both one-dimensional and two-dimensional non-stationary waves. Waves of the first type are supposed to propagate in continuously inhomogeneous, linearly viscoelastic cylinders, whereas waves of the second type propagate in continuously inhomogeneous elastic cylinders. The authors of this chapter apply an original research method consisting of the implementation of solutions to dynamic problems in the study of elastic and linearly viscoelastic piecewise homogeneous bodies. Chapter II outlines an analytical study of the propagation of different types of waves (plane, cylindrical, spherical) as well as of the waves' interaction with an element of Vibro-isolation (specifically, a three-layer plate). The author also presents the numerical results of the study of the distribution of the vibration accelerations in soil. Chapter III presents details on the analytical modeling of a bearing device for passive seismic isolation (friction-pendulum system). The behavior of the slider is identical to a motion of a particle constrained to slide on a spherical surface. The analytical model includes equations of motion, derived using the Lagrange formalism and constitutive equations of the sliding interface. The author presents the results of the numerical simulation of the response of the bearing device to a seismic event, assuming a constant value of the friction coefficient. Chapter IV proposes a discussion on the assessment of the load-carrying capacity of a metal-resin anchor and the determination of dependencies between parameters of supporting systems that include anchors. The solution to the problems addressed in this study involves an accurate analysis of the load transfer mechanisms between different system components. The proposed strategy requires the implementation of an algorithm aimed at the reconstruction of the analytical form of a function, provided its tabular form is available. The authors also formulate a theorem that postulates the existence of such representation applicable in a more general context. The research object in Chapter V is the formulation of the boundary value problems for circular and annular three-layer plates subjected to axisymmetric loading. The considered plates consist of three layers: two thin bearing layers and one filler layer, with a perfect bond, assumed for all interfaces. The definition of the stress-strain state in the plates presumes that the Kirchhoff's hypotheses regarding the bearing layers and the Timoshenko's hypothesis (i.e., linear distribution of the tangential displacements over the thickness) concerning the filler layer hold. The performed analyses take into account the characteristics of the elastic (Winkler) foundation. The authors provide the obtained analytical solutions to the formulated boundary value problems. Results obtained by numerical analysis of the stress and the strain distributions for plates supported by hinges on the contour are also presented.

DKK 718.00
1