Vores kunder ligger øverst på Google

Google Ads Specialister fra Vestjylland

Vi er 100% dedikerede til Google Annoncering – Vi har mange års erfaring med Google Ads og den bruger vi på at opsætte, optimere & vedligeholde vores fantastiske kunders konti.

100% Specialiseret i Google Ads
Vi har mange års erfaring fra +300 konti
Ingen lange bindinger & evighedskontrakter
Jævnlig opfølgning med hver enkelt kunde
Vi tager din virksomhed seriøst

28 resultater (0,28847 sekunder)

Mærke

Butik

Pris (EUR)

Nulstil filter

Produkter
Fra
Butikker

Cloning, Gene Expression and Protein Purification - - Bog - Oxford University Press Inc - Plusbog.dk

Cloning, Gene Expression and Protein Purification - - Bog - Oxford University Press Inc - Plusbog.dk

The central purpose of this combination lecture/laboratory manual is to present detailed protocols for the multi-step process involved in isolating a gene, cloning and characterizing it, expressing the encoded protein, purifying the protein, and characterizing rudimentary aspects of its basic physical properties. The manual includes 20 experiments designed to train students to prepare, manipulate, and analyse plasmids, to produce fusion proteins in bacteria, and to purify these proteins based on unique chemical properties or substrate affinities. Electrophoresis, Southern and Western blotting and cominatorial techniques are emphasized. Radioisotopes, fluorophores and solvent effects on protein structure are discussed. (No radioisotopes are required.) The experiments included have been selected because of their high success rate and because they emphasize a project-oriented approach. Sufficient detail and background are provided such that the intended audience includes advanced undergraduate students, beginning graduates, and practising professionals engaged in a broad range of pursuits. Each experiment is accompanied by detailed process rationale. Where appropriate, alternate methods are also discussed. Maximizing its utility for both studetns and instructors, this unique manual precedes each lab experiment with the necessary background theory and principles, which culminate in a detailed process rationale and, ultimately, the experimental techniques themselves. While many lab manuals list background references, this innovative book combines both theory and procedure into one manageable volume. In addition to this theoretical background material, new innovations and insights are provided along with carefully selected primary source research literature.

DKK 797.00
1

Selection in Natural Populations - Jeffry B. Mitton - Bog - Oxford University Press Inc - Plusbog.dk

Selection in Natural Populations - Jeffry B. Mitton - Bog - Oxford University Press Inc - Plusbog.dk

Flow Cytometry for Biotechnology - - Bog - Oxford University Press Inc - Plusbog.dk

Flow Cytometry for Biotechnology - - Bog - Oxford University Press Inc - Plusbog.dk

Flow cytometry is a sensitive and quantitative platform for the measurement of particle fluorescence. In flow cytometry, the particles in a sample flow in single file through a focused laser beam at rates of hundreds to thousands of particles per second. During the time each particle is in the laser beam, on the order of ten microseconds, one or more fluorescent dyes associated with that particle are excited. The fluorescence emitted from each particle is collected through a microscope objective, spectrally filtered, and detected with photomultiplier tubes. Flow cytometry is uniquely capable of the precise and quantitative molecular analysis of genomic sequence information, interactions between purified biomolecules and cellular function. Combined with automated sample handling for increased sample throughput, these features make flow cytometry a versatile platform with applications at many stages of drug discovery. Traditionally, the particles studied are cells, especially blood cells; flow cytometry is used extensively in immunology. This volume shows how flow cytometry is integrated into modern biotechnology, dealing with issues of throughput, content, sensitivity, and high throughput informatics with applications in genomics, proteomics and protein-protein interactions, drug discovery, vaccine development, plant and reproductive biology, pharmacology and toxicology, cell-cell interactions and protein engineering.

DKK 475.00
1

Flow Cytometry for Biotechnology - - Bog - Oxford University Press Inc - Plusbog.dk

Flow Cytometry for Biotechnology - - Bog - Oxford University Press Inc - Plusbog.dk

Flow cytometry is a sensitive and quantitative platform for the measurement of particle fluorescence. In flow cytometry, the particles in a sample flow in single file through a focused laser beam at rates of hundreds to thousands of particles per second. During the time each particle is in the laser beam, on the order of ten microseconds, one or more fluorescent dyes associated with that particle are excited. The fluorescence emitted from each particle is collected through a microscope objective, spectrally filtered, and detected with photomultiplier tubes. Flow cytometry is uniquely capable of the precise and quantitative molecular analysis of genomic sequence information, interactions between purified biomolecules and cellular function. Combined with automated sample handling for increased sample throughput, these features make flow cytometry a versatile platform with applications at many stages of drug discovery. Traditionally, the particles studied are cells, especially blood cells; flow cytometry is used extensively in immunology. This volume shows how flow cytometry is integrated into modern biotechnology, dealing with issues of throughput, content, sensitivity, and high throughput informatics with applications in genomics, proteomics and protein-protein interactions, drug discovery, vaccine development, plant and reproductive biology, pharmacology and toxicology, cell-cell interactions and protein engineering.

DKK 737.00
1

Neuromodulation - - Bog - Oxford University Press Inc - Plusbog.dk

Phylogenetic Trees Made Easy - Barry G. Hall - Bog - Oxford University Press Inc - Plusbog.dk

Seeking Cures - Moyra Smith - Bog - Oxford University Press Inc - Plusbog.dk

Perl for Exploring DNA - Mark Le Blanc - Bog - Oxford University Press Inc - Plusbog.dk

The Meaning of Disgust - Colin Mcginn - Bog - Oxford University Press Inc - Plusbog.dk

A Place in History - Paul M. (professor Of Cell Wassarman - Bog - Oxford University Press Inc - Plusbog.dk

Beyond the Finite - - Bog - Oxford University Press Inc - Plusbog.dk

The Implicit Genome - - Bog - Oxford University Press Inc - Plusbog.dk

DKK 546.00
1

Clinical Studies in Medical Biochemistry - - Bog - Oxford University Press Inc - Plusbog.dk

Clinical Studies in Medical Biochemistry - - Bog - Oxford University Press Inc - Plusbog.dk

This text uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 33 cases are carefully selected to cover key concepts and common diseases. Each chapter provides a specific patient report that includes the relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease.In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focussed on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutrional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism.The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.

DKK 562.00
1

Clinical Studies in Medical Biochemistry - - Bog - Oxford University Press Inc - Plusbog.dk

Clinical Studies in Medical Biochemistry - - Bog - Oxford University Press Inc - Plusbog.dk

This text uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 33 cases are carefully selected to cover key concepts and common diseases. Each chapter provides a specific patient report that includes the relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease.In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focused on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutrional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism.The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.

DKK 1149.00
1

Back in the Game - Joanne C. Gerstner - Bog - Oxford University Press Inc - Plusbog.dk

Back in the Game - Joanne C. Gerstner - Bog - Oxford University Press Inc - Plusbog.dk

The word concussion used to be unheard of in youth sports a decade ago. The brain injury was indeed occurring, but coaches and parents were encouraging their youth athletes to "shake it off" after "getting their bell rung". Science and increased awareness about concussion are transforming the way youth parents, coaches, and players pursue athletics. Fear of incurring concussions, as well as incorrect information, is leading some parents to keep their children out of contact sports, such as football and soccer, where concussion is more prevalent.Back in the Game: Why Concussion Doesn''t Have to End Your Athletic Career does not dwell on perpetuating fears, but rather, provides the most up-to-date understanding of the condition. This text includes a real-world discussion of what science and medicine knows, what parents and coaches need to understand about concussions, evaluation and treatment, and possible post-concussive issues, like depression. At the heart of this book, the authors delve into these issues, explaining them in a clear and understandable way.The expertise and experiences of noted sports neurologist Jeffrey Kutcher, MD, along with reporting and interviews by award-winning sports journalist Joanne C. Gerstner, makes this book a timely, relevant, and real discussion about concussions in youth sports. Athletes and professional coaches who have participated in the formation of this book include two-time Olympic gold medalist soccer player Kate Markgraf, former NHL/Team Canada head coach Andy Murray, champion X-Games snowboarder Ellery Hollingsworth, along with an array of youth parents, coaches, and athletes from across the country.

DKK 377.00
1

On Taking Offence - Emily Mcternan - Bog - Oxford University Press Inc - Plusbog.dk

On Taking Offence - Emily Mcternan - Bog - Oxford University Press Inc - Plusbog.dk

Someone fails to shake your outstretched hand, puts you down in front of others, or makes a joke in poor taste. Should we take offence? Wouldn''t it be better if we didn''t? In the face of popular criticism of people taking offence too easily, and the social problems that creates, Emily McTernan defends taking offence as often morally appropriate and socially valuable. Within societies marred by inequality, taking offence can resist the day-to-day patterning of social hierarchies. This book defends the significance of details of our social interactions. Cumulatively, small acts, and the social norms underlying these, can express and reinforce social hierarchies. But by taking offence, we mark an act as an affront to our social standing. We also often communicate our rejection of that affront to others. At times, taking offence can be a way to renegotiate the shared social norms around what counts as respectful treatment. Rather than a mere expression of hurt feelings then, to take offence can be to stand up for one''s standing. When taken by those deemed to have less social standing, to take offence can be a direct act of insubordination against a social hierarchy. Taking offence can resist everyday inequalities. In unequal societies, the inclination to take offence at the right things, and to the right degree, may even be a civic virtue. These right things at which to take offence include many of the very instances that the opponents of a culture of taking offence find most objectionable: apparently trivial and small-scale details of our social interactions.

DKK 282.00
1

On Taking Offence - Emily Mcternan - Bog - Oxford University Press Inc - Plusbog.dk

On Taking Offence - Emily Mcternan - Bog - Oxford University Press Inc - Plusbog.dk

Someone fails to shake your outstretched hand, puts you down in front of others, or makes a joke in poor taste. Should we take offence? Wouldn''t it be better if we didn''t? In the face of popular criticism of people taking offence too easily, and the social problems that creates, Emily McTernan defends taking offence as often morally appropriate and socially valuable. Within societies marred by inequality, taking offence can resist the day-to-day patterning of social hierarchies. This book defends the significance of details of our social interactions. Cumulatively, small acts, and the social norms underlying these, can express and reinforce social hierarchies. But by taking offence, we mark an act as an affront to our social standing. We also often communicate our rejection of that affront to others. At times, taking offence can be a way to renegotiate the shared social norms around what counts as respectful treatment. Rather than a mere expression of hurt feelings then, to take offence can be to stand up for one''s standing. When taken by those deemed to have less social standing, to take offence can be a direct act of insubordination against a social hierarchy. Taking offence can resist everyday inequalities. In unequal societies, the inclination to take offence at the right things, and to the right degree, may even be a civic virtue. These right things at which to take offence include many of the very instances that the opponents of a culture of taking offence find most objectionable: apparently trivial and small-scale details of our social interactions.

DKK 805.00
1

From Farm to Table - Alan Kelly - Bog - Oxford University Press Inc - Plusbog.dk

From Farm to Table - Alan Kelly - Bog - Oxford University Press Inc - Plusbog.dk

The consumption of dairy products, made from the milk of cows, sheep, goats and buffalo, among other mammalian species, is almost as old as human civilization, with evidence of these products stretching back many millenia. The production of different kinds of dairy products originated as different ways to preserve the valuable nutritional goodness of milk components (lactose, fat, protein, vitamins and minerals) and make the milk safe for consumption, using basic principles like fermentation, heating, separation, dehydration, acidification, smoking and salting, which are the keys to producing products like cheese, butter and yogurt. Many dairy products today are still produced using the same basic principles, and in this book an introduction to the origins, constituents and properties of milk is given, alongside an outline of the ways in which dairy products are made including the development of advanced products like infant formula and formulated nutritional products. The text introduces, at an introductory level, the chemistry and microbiology of milk, as well as the principles of the main processes used like spray-drying, fermentation and pasteurization, to underpin understanding of how the properties of the main dairy products emerge. The book, which finishes with a discussion of the challenges and threats facing dairy today, is designed to be accessible to a wide range of non-specialist readers who may have an interest in milk and dairy products and want to learn more about this fascinating and ancient branch of the science of food.

DKK 291.00
1

Verdun - Paul Jankowski - Bog - Oxford University Press Inc - Plusbog.dk

Verdun - Paul Jankowski - Bog - Oxford University Press Inc - Plusbog.dk

At seven o''clock in the morning on February 21, 1916, the ground in northern France began to shake. For the next ten hours, twelve hundred German guns showered shells on a salient in French lines. The massive weight of explosives collapsed dugouts, obliterated trenches, severed communication wires, and drove men mad. As the barrage lifted, German troops moved forward, darting from shell crater to shell crater. The battle of Verdun had begun. In Verdun, historian Paul Jankowski provides the definitive account of the iconic battle of World War I. A leading expert on the French past, Jankowski combines the best of traditional military history-its emphasis on leaders, plans, technology, and the contingency of combat-with the newer social and cultural approach, stressing the soldier''s experience, the institutional structures of the military, and the impact of war on national memory. Unusually, this book draws on deep research in French and German archives; this mastery of sources in both languages gives Verdun unprecedented authority and scope. In many ways, Jankowski writes, the battle represents a conundrum. It has an almost unique status among the battles of the Great War; and yet, he argues, it was not decisive, sparked no political changes, and was not even the bloodiest episode of the conflict. It is said that Verdun made France, he writes; but the question should be, What did France make of Verdun? Over time, it proved to be the last great victory of French arms, standing on their own. And, for France and Germany, the battle would symbolize the terror of industrialized warfare, "a technocratic Moloch devouring its children," where no advance or retreat was possible, yet national resources poured in ceaselessly, perpetuating slaughter indefinitely.

DKK 152.00
1

The Scleroderma Book - Maureen D. Mayes - Bog - Oxford University Press Inc - Plusbog.dk

The Scleroderma Book - Maureen D. Mayes - Bog - Oxford University Press Inc - Plusbog.dk

Scleroderma means hardening of the skin, due to a malfunction of the vascular and immune system resulting in the overproduction of collagen (a protein substance found in the body''s connective tissue). In this second edition of The Scleroderma Book, Dr Maureen Mayes - the leading authority in the field - draws on her extensive experience treating scleroderma to provide up-to-date, practical information that will help patients manage their symptoms and improve their quality of life.Scleroderma can be localized (small patches of hardened skin, which tend to clear up over time), but may become systemic with excess collagen building up in various organs such as the oesophagus, kidneys, lungs, gastrointestinal tract, heart skin, and peripheral nervous system. The disorder most commonly occurs in women between the ages of 20 and 40. However, men and children can be affected as well. The disease is not contagious and is not thought to be inherited and currently, there is no known cure.Writing specifically for patients and their families, Dr. Mayes offers sympathetic and reassuring advice on matters that often concern those living with scleroderma, such as the best course of action for those who want children, what to do if the disease affects your sex life, and what you can do to help your doctor treat your illness more effectively. The book concludes with a good humoured, frank discussion about how to cope, day in and day out, with an uncertain future--how to be a "person living with" scleroderma, not a "victim suffering from" it. Touching on virtually every aspect of this disorder, The Scleroderma Book provides a reliable source of information and reassurance for patients of any age, no matter how severe their form of the disease.

DKK 250.00
1

Meet the Food Radicals - Tamara L. Mix - Bog - Oxford University Press Inc - Plusbog.dk

Meet the Food Radicals - Tamara L. Mix - Bog - Oxford University Press Inc - Plusbog.dk

The food system has changed considerably in the last century. Horsepower was replaced by machine, better crop breeding programs helped usher in the Green Revolution, and problems of malnutrition began to run parallel with those of obesity. Despite changes, many of the problems we face remain the same. Farms continue to lose soil, and low income households still have difficulty acquiring healthy food. Add to these challenges a host of new ones. Globalization has caused some agricultural communities to feel threatened. Everyone recognizes problems of malnutrition, obesity and food sustainability, but many disagree on solutions. One thing is certain: confronting both familiar and new challenges will lead to radical changes in the food system. Though the exact form of radical change is unknown, this book looks to a host of candidates by interviewing the people who champion them. We are winning the battle against soil erosion through new no-till farming methods. Progress is being made in food sustainability by a spectrum of new innovations, but also a return to traditional farming techniques. New innovations include robots on the farm, advances in molecular biology, and alternative protein sources. As we embrace the farming strategies of our ancestors, we see farms returning to polycultures, local food systems, and food sovereignty. This book gains insight from interviews with twenty-seven individuals who are either creating or proposing radical changes in how food is produced and distributed. An eclectic group ranging from farmers to activists to spiritual gurus, they are the most interesting people you have never met. By getting to know each "radical" personally we can better access their voices and visions to understand both the problems and likely solutions to today''s most pressing food problems.

DKK 329.00
1

Quantum Monte Carlo - James B. Anderson - Bog - Oxford University Press Inc - Plusbog.dk

Quantum Monte Carlo - James B. Anderson - Bog - Oxford University Press Inc - Plusbog.dk

Monte Carlo methods are a class of computational algorithms for simulating the behavior of a wide range of various physical and mathematical systems (with many variables). Their utility has increased with general availability of fast computers, and new applications are continually forthcoming. The basic concepts of Monte Carlo are both simple and straightforward and rooted in statistics and probability theory, their defining characteristic being that the methodology relies on random or pseudo-random sequences of numbers. It is a technique of numerical analysis based on the approximate solution of a problem using repeated sampling experiments and observing the proportion of times a given property is satisfied. The term Monte Carlo was first used to describe calculational methods based on chance in the 1940s, but the methods themselves preceded the term by as much as a century. Quantum Monte Carlo (QMC) first appeared in 1982 and similarly was preceded by development of the related calculational methodology. The success of QMC methods over the past few decades has been remarkable, and this book will clearly demonstrate that success in its discussion of applications. For isolated molecules, the basic material of chemistry, QMC methods have produced exact solutions of the Schroedinger equation for very small systems and the most accurate solutions available for very large systems. The range of applications is impressive: folding of protein molecules, interactions in liquids, structure modeling in crystals and enzymes, quantum dots, designing heat shields and aerodynamic forms, architecture, design, business and economics, and even cinema and video games (3D modeling). This book takes a similar approach to Henry Schaefers classic book Quantum Chemistry (OUP, 1984 now a Dover edition), collecting summaries of some of the most important papers in the quantum Monte Carlo literature, tying everything together with analysis and discussion of applications. Quantum Monte Carlo is a reference book for quantum Monte Carlo applications, belonging near the desk of every quantum chemist, physicist, and a wide range of scientists and engineers across many disciplines, destined to become a classic.

DKK 933.00
1

Excitatory Amino Acid Transmission in Health and Disease - Carl W. Cotman - Bog - Oxford University Press Inc - Plusbog.dk

Excitatory Amino Acid Transmission in Health and Disease - Carl W. Cotman - Bog - Oxford University Press Inc - Plusbog.dk

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS). It regulates normal CNS function, is a major participant in pathology, and serves learning, memory, and higher cognitive functions. The 12 chapters of this book provide the first comprehensive coverage of all the major features of glutamate as excitatory neurotransmitter. The book begins with a valuable historical backdrop. Building from a chapter on the common structure of glutamate receptors, several others cover the major ionotropic receptors, their structure, function, and pharmacology. A follow-up chapter discusses the metabotropic receptors that are directly coupled to second messenger metabolism.A central theme of the book is the capacity of the excitatory amino acid system to contribute to the diverse array of signaling systems in the CNS as a direct result of the large assortment of receptors (including, for the ionotropic receptors, various subunits) the combination of which determine distinct functional properties. A recent development in the field discussed in several chapters is the biochemical characterization of a supermolecular protein complex, the post-synaptic density, that makes the unique structure of excitatory synapses. This complex subserves the experience-dependent modulation of synaptic strength and synaptic plasticity, and gives the synapse the capacity to change dynamically in both structure and receptor composition. Drawing on the individual properties of the receptors, transporters, and functional architecture of the synapse, the concluding chapters describe the functional integration of these components in the more complex physiological processes of plasticity and pathology. Recognition that the regulation of excitatory amino acid receptor activity underlies the pathology of many neurological diseases, including stroke, Alzheimer''s disease and schizophrenia, has opened up an exciting frontier that will allow the translation of our understanding of these basic mechanisms into new concepts of pathology and new therapeutic strategies. This book will be invaluable for neuroscientists, pharmacologists, neurologists, and psychiatrists, and for their students and trainees.

DKK 1049.00
1

Phenotypic Variation - Moyra Smith - Bog - Oxford University Press Inc - Plusbog.dk

Phenotypic Variation - Moyra Smith - Bog - Oxford University Press Inc - Plusbog.dk

During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on aspects of phenotypic variation. The goal of functional genomics is to gain insight into mechanisms through which specific changes in genome transcripts and regulation induce changes in proteins, pathways, organelles, cellular and tissue functions, morphology and ultimately in phenotype. Topics reviewed include investigations in genome architecture, gene structure, gene regulation epigenetic modifications and function of organelles including mitochondria, and the endosome lysosome system. New insights into neurodevelopment and neurobehavioral disorders gained through functional genomic research are presented. Aspects of genomic studies in complex common diseases are reviewed. Molecular genetic variations and aberrations in cellular mechanisms involved in protein quality surveillance play a role in late onset diseases and one chapter deals with this topic. Molecular analyses of genes and proteins continue to shed light on the pathogenesis of malformation syndromes and specific examples of such studies are presented. There is growing evidence that late onset disorders such as Parkinson disease, are frequently the end result of defects in functioning of components in different pathways and examples of these are discussed. There is evidence that genetic variation determines differences in response to environmental insults. Genetic variations in complement factor genes are an example of this and are discussed in the context of macular degeneration and pathogenesis of hemolytic uremic syndrome in response exposure to E coli Shiga toxin. In the final chapter the author briefly summarizes key features of the cascade of events that constitute functional genomics.

DKK 903.00
1