Nitrergic system activity in acute toxic hepatitis - Alisher Orypovych Ohunov

This monograph presents the results of comprehensive studies performed in in vivo experiments on animals with CCl4 (fatty hepatosis) and heliotrine (protein dystrophy) acute toxic hepatitis. For the first time, it was found that high inhibition of calmodulin-dependent eNOS activity and stimulation of calmodulin-independent iNOS, further initiates NO formation and increases ONO2-. In-depth study of the relationship between oxidative stress, nitrergic system and apoptosis development factors can clarify..