The role of protein glycation - Anago Ahoefa A. Eugénie

The binding of an ose, frequently glucose, to proteins is a common biochemical reaction leading to the formation of Advanced Glycation Endproducts (AGEs). The permanent hyperglycemia observed during diabetes leads to an increase in the glycation rate of proteins, with consequent impairment of their functions. Several authors have demonstrated the link between the accumulation of AGEs in various organs and the microvascular and macrovascular complications observed in diabetes. Other studies have shown..