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Bringing a Medical Device to the Market A Scientist’s Perspective

Bringing a Medical Device to the Market A Scientist’s Perspective

Many of us in science have this Aha! moment when the mental puzzle is put together and you get a clear picture of a product which will change the world. Moreover you have a clear understanding of how it can be a commercial success. So you decide to start a new company a startup and have a clear path to success. However soon you come face to face with reality where things are much more complicated. Only a minute fraction of startups survives and becomes successful. This is particularly true in the complex world of medical devices. There are many good books on startups but this book is specifically about startups specializing in medical devices which are very different from other ones. It is written by a MedDev entrepreneur for first-time MedTech entrepreneurs. | Bringing a Medical Device to the Market A Scientist’s Perspective

GBP 76.99
1

Musical Spaces Place Performance and Power

Musical Spaces Place Performance and Power

There is growing recognition and understanding of music’s fundamentally spatial natures with significances of space found both in the immediacy of musical practices and in connection to broader identities and ideas around music. Whereas previous publications have looked at connections between music and space through singular lenses (such as how they are linked to ethnic identities or how musical images of a city are constructed) this book sets out to explore intersections between multiple scales and kinds of musical spaces. It complements the investigation of broader power structures and place-based identities by a detailed focus on the moments of music-making and musical environments revealing the mutual shaping of these levels. The book overcomes a Eurocentric focus on a typically narrow range of musics (especially European and North American classical and popular forms) with case studies on a diverse set of genres and global contexts inspiring a range of ethnographic text-based historical and practice-based approaches. | Musical Spaces Place Performance and Power

GBP 76.99
1

Art Conservation Mechanical Properties and Testing of Materials

Art Conservation Mechanical Properties and Testing of Materials

Conservators and other museum professionals face a large number of issues involving the mechanical behavior of materials including questions on craquelure restoring physically damaged objects art in transport or the selection of adhesives. However science in conservation and museum studies curricula focusses mostly on chemistry. This book fills this important gap in conservation training. It is the first such book written specifically for the conservation community and professionals with little or no background in (mechanical) engineering. It introduces the basics of mechanical properties and behavior of materials and objects with examples and exercises based on conservation practice. More complex issues of mechanical loading and advanced solutions are also introduced. | Art Conservation Mechanical Properties and Testing of Materials

GBP 100.00
1

Conjugated Objects Developments Synthesis and Applications

Conjugated Objects Developments Synthesis and Applications

Conjugated Objects: Development Synthesis and Application contains 17 chapters written by young researchers and contains current trends in pi-conjugated systems for application in broad research areas such as design of unique pi-conjugation catalysts self-assembly charge transfer complexes liquid crystals supramolecules and nanostructures by using conjugated small and/or macro-objects organically or electrochemically. The book can be used as a textbook of basic learning by undergraduate and graduate students of chemistry electrical and electronics engineering and materials science and by supramolecular researchers in nanotechnology and biotechnology. | Conjugated Objects Developments Synthesis and Applications

GBP 114.00
1

Self-Aware Robots On the Path to Machine Consciousness

Self-Aware Robots On the Path to Machine Consciousness

This book focuses on the research and development in the field of self-aware robots. Its theme is artificial consciousness a field that covers both artificial intelligence and robotics and includes philosophy psychology the study of biological evolution physiology and medicine especially brain neuroscience and neuropsychiatry. Building on the first edition Creation of a Conscious Robot: Mirror Image Cognition and Self-Awareness this new edition discusses artificial neural networks and functions of human consciousness. It proposes a structure for a neural network with consciousness functions explains the construction of a conscious system and discusses the results of progressive research in designing and developing small robots with conscious systems capable of recognizing their own images in mirrors. Emphasizing the contributions of conscious robots to society and their potential future impact the book also describes the robots that know the unknown Pavlovian robots and the development of a consciousness model possessing the well-known multiple personality disorder. | Self-Aware Robots On the Path to Machine Consciousness

GBP 100.00
1

Nitric Oxide Sensing

Nitric Oxide Sensing

Although nitric oxide (NO) is an important biological signaling molecule its free-radical electronic configuration makes it a most reactive molecule and the scariest colorless gas causing immense environmental and health hazards. Detection of NO levels in biological samples and in the atmosphere is therefore crucial. In the past few years extensive efforts have been devoted to developing many active sensors and effective devices for detecting and quantifying atmospheric NO NO generated in biological samples and NO exhaled in the human breath. This book provides a concrete summary of recent state-of-the-art small-molecule probes and novel carbon nanomaterials used for chemical photoluminescent and electrochemical NO detection. One chapter is especially dedicated to the available devices used for detecting NO in the human breath that indirectly infers to lung inflammation. The authors with expertise in diverse dimensions have attempted to cover almost all areas of NO sensing. | Nitric Oxide Sensing

GBP 116.00
1

Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

This volume of Pharmaceutical Biocatalysis starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types; human DOPA decarboxylase related to Parkinson's disease and aromatic amino acid decarboxylase deficiency; and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. An additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors targeting receptor tyrosine kinases in cancer β-Lactams and related compounds as antibacterials non-vitamin K oral anticoagulants for the treatment of thromboembolic diseases and the molecular mechanisms for statin pleiotropy and its clinical relevance in cardiovascular diseases. The last chapter is a review of lysosomal storage disorders with an overview of approved drugs for treating these disorders by enzyme replacement therapy. | Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

GBP 193.00
1

Bionanotechnology in Cancer Diagnosis and Therapy

Bionanotechnology in Cancer Diagnosis and Therapy

The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles magnetic nanoparticles acoustically reflective nanoparticles X-ray computed tomography and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy magnetic nanoparticles for hyperthermia against cancer phototherapy nanotechnology-mediated radiation therapy nanoparticle-mediated small-RNA deliveries for molecular therapies and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience which is considered the last hope for the fight against cancer and will be a highly useful resource for the students researchers teachers and curious readers working in this field or related fields. | Bionanotechnology in Cancer Diagnosis and Therapy

GBP 154.00
1

Physics and Future of Hurricanes

Physics and Future of Hurricanes

This monograph is about hurricanes prompted by a discovery that suggests they will become more powerful with global warming. It provides at a college physics level a basic understanding of hurricanes emphasizing the flow of energy into and out of these storms and as a textbook covers some material that might be taught in meteorology or atmospheric physics courses. The text is centered on a new discovery that is not in any existing textbook. Because of the new discovery the book is of immediate interest to all meteorologists. It turns out that hurricanes as revealed by the new discovery are usefully regarded as a separate phase of matter bringing in characteristic temperature dependences near their transitions. The role of phase change in understanding hurricanes brings in the 20th-century discoveries in theoretical physics relating to critical phenomena with non-intuitive values of the critical exponent β entering the formula P = const (T – Tc)β where P is a characteristic strength parameter or order parameter of the phase of matter appearing at Tc. According to the new discovery on hurricanes it appears that taking the wind velocity as the order parameter P the critical exponent is near 1/3. In a second discovery we find that a small correction to this value is brought in by the complicated physics of the renormalization group that earned K. G. Wilson the Nobel Prize in Physics in 1982. | Physics and Future of Hurricanes

GBP 53.99
1

Mobile Microspies Particles for Sensing and Communication

Mobile Microspies Particles for Sensing and Communication

On the one hand particle-based sensing techniques are driven by new technologies for preparing and measuring micro- and nanoparticles and by a fascination of the possibilities for design and functionalization of all specificities in structure shapes and behavior of these tiny objects. On the other hand there evolves a fast-growing need for new sensing and communication paths for medicine biotechnology and analytical science as well as for new and efficient information transfer and storage systems. No longer are particles regarded only as special types of materials. However we have a better understanding of how they are bridging the gap between material and system between structure and function. Although there are numerous books on micro- and nanoparticles and on sensors there is to the best of my knowledge no book focusing on the general concept of particles as mobile microtransducers. This book clarifies that signal-transducing particles should be regarded as functional elements as part of a system not simply as special materials. It introduces concepts of bead-base sensing and mobile spies at the micro- and nanoscale and gives a representative overview of the variety of particle-based sensing. The state of the art in the development of particles as mobile spies for communication and information management allows us to speculate about future particle-based components and systems in a completely sustainable world economy. In addition the book reports on a fast-evolving technical field which is a typical example of the required convergence of technical strategies and mechanisms in living nature and would make a great reference for professionals and students of chemistry biochemistry biology pharmacy medicine agriculture mechatronics informatics materials science and systems engineering. | Mobile Microspies Particles for Sensing and Communication

GBP 100.00
1