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Three Daughters Three Journeys Quest for Cancer Cure

Three Daughters Three Journeys Quest for Cancer Cure

Cancer threatens the lives of people around the world. Women in particular are at risk of certain cancers with a genetic cause. Certain mutations in the BRCA1 and BRCA2 genes put mothers and daughters at risk of breast and ovarian cancers. Unlike many cancers that most commonly occur after age 60 these inheritable cancers threaten women’s lives health and fertility even when they are young before most would even begin to go for annual mammogram screenings to check for breast cancer. Three Daughters Three Journeys takes on the biggest health issue of our time from a global perspective with three heroines fighting for their lives against cancer. Marzena a Polish oncology nurse has spent her life treating child patients with cancer. Then she confronts it in her own family and her own body. Kamola a rural Indian girl knows she has symptoms of the same disease that took her mother but feels afraid to discuss it with her father and brothers knowing her family cannot afford medical treatment. Kamola confides in Dr Rini Mishra a doctor testing a new treatment called Neelazin using a bacterial anticancer protein in food to destroy cancer cells. Selena a wealthy woman of color in Chicago finds out about her genetic risks of breast and ovarian cancer. She has a choice of preventative surgery that will save her life but remove any chance of having children. As she meets women who struggle to afford cancer treatment Selena dedicates her life to providing affordable homes and counseling to families affected by the disease. Although the drug Neelazin is fictional the possibility of new cancer treatments using bacterial anticancer proteins is being researched now. A problem with the current chemotherapy for cancer treatment is the high toxicity of most of these drugs as these drugs can enter both normal and cancer cells though preferably cancer cells causing the death of normal cells as well that are important in maintaining health. Another problem is that current chemotherapeutic drugs mostly target a single or few key steps that are important for cancer growth and proliferation and inhibit the growth of cancer cells. The cancer cells respond by quickly changing these single targets thereby becoming resistant to the drugs as is reflected in stage IV cancer patients. An alternative to chemotherapy would be to exploit the bacterial evolutionary wisdom and use certain proteins that can have preferential entry to cancer cells in order to minimize normal cell toxicity and multiple targets in cancer cells through protein–protein complex formation thus reducing resistance development in cancer cells. An interesting advantage of protein drugs is to express them as part of food and some recent research seems to suggest that oral consumption of such foods may allow the therapeutic protein to reach the blood stream to target the cancer. Women with the genetic risk factors could soon have the choice of taking a pill or such anticancer protein-expressing food to treat or prevent cancer rather than removing the healthy tissue of the breasts and ovaries. Hopefully they would not have to choose between fertility and survival as is the implied message in this book fictional as it is at this time. | Three Daughters Three Journeys Quest for Cancer Cure

GBP 31.99
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RNA the Epicenter of Genetic Information

RNA the Epicenter of Genetic Information

The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein the underestimation of the amount of information required to program the development of multicellular organisms and the dawning realization that RNA is the cornerstone of cell biology development brain function and probably evolution itself. Key personalities their hubris as well as prescient predictions are richly illustrated with quotes archival material photographs diagrams and references to bring the people ideas and discoveries to life from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book available at www. taylorfrancis. com has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4. 0 license. | RNA the Epicenter of Genetic Information

GBP 39.99
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How to Create a Sustainable Food Industry A Practical Guide to Perfect Food

How to Create a Sustainable Food Industry A Practical Guide to Perfect Food

This book presents a practical guide to help businesses navigate the complex topics of sustainability in the food industry. The book takes you on a journey along the food value chain from farm to fork exploring key opportunities to increase positive impacts and circularity at each step of the journey. Written by a team of authors with decades of experience in the food industry and academia it provides guidance on how to analyse sustainability across the value chain and life cycle of a food product and how to design implement and communicate strategies to customers. Furthermore the book shows that there are not always straightforward solutions but rather choices and trade-offs that require an understanding of what is best suited to the product customers and business in question. It demystifies a variety of topics such as local sourcing regenerative agriculture plant-based protein and the environmental impact of meat production and draws on a wide range of case studies from across the globe to provide concrete real-world examples. While a perfect food system may not exist informed decisions can go a long way to reshape and transform the food industry as we know it. This book will be of great interest to professionals working in the food and agriculture industries as well as students and scholars of sustainable food systems and sustainable business. | How to Create a Sustainable Food Industry A Practical Guide to Perfect Food

GBP 31.99
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