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Multi-Dimensional Liquid Chromatography Principles Practice and Applications

Multi-Dimensional Liquid Chromatography Principles Practice and Applications

Two-dimensional liquid chromatography (2D-LC) is finding increasingly wide application principally due to the analysis of mixtures of moderate to high complexity. Many industries are developing increasingly complex products that are challenging the separation capabilities of state-of-the-art 1D-LC and need new analytical methodologies with substantially more resolving power and 2D-LC meets that need. This text organized by two leaders in the field establishes a sound fundamental basis for the principles of the technique followed by a discussion of important practical considerations. The book begins with an introduction to multi-dimensional separations and a discussion of the history and development of the technique over the past 40 years followed by several chapters that provide a theoretical basis for development of 2D-LC methods including foundational concepts regarding separation complementarity under-sampling and dynamics of liquid chromatography separations. Instrumentation for 2D-LC is discussed extensively including practical aspects such as interface selection and setup. Building on this foundation two separate chapters are focused on method development for non-comprehensive and comprehensive separations followed by a chapter dedicated to data analysis. Finally applications of 2D-LC in several fields ranging from pharmaceutical analysis to polymer science are summarized. The book is an important resource for both students and practitioners who are already using 2D-LC or are interested in getting started in the field. Key Features: Demonstrates the conditions under which a 2D-LC method should be considered as an alternative to a 1D-LC method Establishes a sound fundamental basis of the principles of the technique followed by guidelines for method optimization Provides a single source for technical knowledge advances and practical guidance described in recent literature Assists with the initial decision to develop a 2D-LC method Guides the reader in developing a high-quality method that meets the needs of their application | Multi-Dimensional Liquid Chromatography Principles Practice and Applications

GBP 180.00
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Routledge International Handbook of Police Ethnography

Routledge International Handbook of Police Ethnography

Ethnography has a long history in the humanities and social sciences and has provided the base line in the field of police studies for over 60 years. We have recently witnessed a resurgence in ethnographic practice among police scholars and this Handbook is a response to that revival. Students and academics are returning to the ethnography arena and the study of police in situ to explain the evocative worlds of the police. The list of ethnographic sites is vast and all have fed the rejuvenation of ethnographic endeavour. Together they suggest innovation theoretical depth broad geographical boundaries multi-site experiments and multi-disciplinarity all of which are central to the exploration of police and policing in the twenty-first century. This Handbook encapsulates the revival of police ethnography by exploring its multidisciplinary field and cataloguing the ongoing ethnographic work. It offers an original and international contribution to the field of police studies and research methods providing a comprehensive and overarching guide to police ethnography. We see the previous classics in every page and still note the influence of the early ethnographers. At the same time we see the innovative breadth and diversity of these narratives. The aim of this Handbook is to highlight the mosaic that is police ethnography at a point in time and note with pleasure its contribution to the field once more. Ethnography may be messy difficult and at times uncooperative but its results offer a unique insight into the perspectives of people and organisations that can hide in plain sight. An accessible and compelling read this Handbook will provide a sound and essential reference source for academics researchers students and practitioners engaged in police and criminal justice studies. | Routledge International Handbook of Police Ethnography

GBP 190.00
1

Routledge Handbook on the Modern Maghrib

Rodent Pest Management

Handbook of Sustainable and Integrative Manufacturing Technologies

The Routledge Companion to Global Literary Adaptation in the Twenty-First Century

Routledge Handbook of Chinese Business and Management

The Routledge Companion to William Morris

The Routledge Handbook of Geospatial Technologies and Society

Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications Second Edition

CRC World Dictionary of Palms Common Names Scientific Names Eponyms Synonyms and Etymology (2 Volume Set)

CRC World Dictionary of Palms Common Names Scientific Names Eponyms Synonyms and Etymology (2 Volume Set)

From the ForewordUmberto Quattrocchi has brought us some amazing and useful works through the various dictionaries that he has compiled. This time it is for two very important plant families the palms and the cycads that are synthesized here in these two volumes. Each entry is fascinating not just for the botany and full nomenclature of the plant species but for all the associated uses folklore and interactions with other organisms. . These entries are fascinating glimpses of natural history. . Botanists conservationists ethnobotanists anthropologists geographers bird watchers naturalists historians and those of many other disciplines will find these volumes a most valuable and useful resource. It is the sort of book that will be in frequent use in my library. - Professor Sir Ghillean Prance FRS VMH Former Director Royal Botanic Gardens Kew Following the same format as Umberto Quattrocchi’s highly praised and well-used previous works The CRC World Dictionary of Palms: Common Names Scientific Names Eponyms Synonyms and Etymology brings together the vast and scattered literature on palms and cycads to provide better access to information on these economically important plants. Each genus and species has a detailed morphological description and includes a list of synonyms and vernacular names in many languages. Bibliographies accompany each entry which are comprehensive up-to-date and multi-lingual. The detailed information for every entry on habitats economic uses historical and biographical data botanical exploration and linguistics will be useful for any library involved with botany herbal medicine pharmacognosy medicinal and natural product chemistry ecology ethnobotany systematics general plant science agriculture or horticulture. Umberto Quattrocchi is the author of the bestselling CRC World Dictionary of Plant Names winner of the prestigious Hanbury Botanical Garden Award. His most recent multi-volume work CRC World Dictionary of Medicinal and Poisonous Plants received strong praise as being . an unparalleled starting place—a tool of first resort for any thoughtful researcher. Quattrocchi and CRC have delivered a dictionary like no other a learned finger pointing in the right direction. —John de la Parra Northeastern University Boston Massachusetts USA from Economic Botany Vol. 68 2014 | CRC World Dictionary of Palms Common Names Scientific Names Eponyms Synonyms and Etymology (2 Volume Set)

GBP 300.00
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Boiler Operator's Handbook

The New Web Typography Create a Visual Hierarchy with Responsive Web Design

Routledge Handbook of South Asian Migrations

Substance Abuse Assessment and Diagnosis A Comprehensive Guide for Counselors and Helping Professionals

Armed Conflict Survey 2018

The Routledge Handbook of Global Development

GBP 205.00
1

Routledge Handbook of Chinese Architecture Social Production of Buildings and Spaces in History

Routledge Handbook of Chinese Architecture Social Production of Buildings and Spaces in History

This handbook representing the collaboration of 40 scholars provides a multi-faceted exploration of roughly 6 000 years of Chinese architecture from ancient times to the present. This volume combines a broad-spectrum approach with a thematic framework for investigating Chinese architecture integrating previously fragmented topics and combining the scholarship of all major periods of Chinese history. By organizing its approach into five parts this handbook: Traces the practices and traditions of ancient China from imperial authority to folk culture Unveils a rich picture of early modern and republican China revealing that modernization was already beginning to emerge Describes the social intellectual ideological and formal enterprises of socialist architecture Frames a window on a complex and changing contemporary China by focusing on autonomy state practices and geopolitics of design ultimately identifying its still evolving position on the world stage Examines the existing cultural and political theories to highlight potential avenues for future transformations in Chinese architecture that also retain Chinese identity Providing a pioneering combination of ancient and modern Chinese architecture in one coherent study this book is a must-read for scholars students and educators of Chinese architecture architectural history and theory and the architecture of Asia. | Routledge Handbook of Chinese Architecture Social Production of Buildings and Spaces in History

GBP 190.00
1

Routledge Handbook of Francophone Africa

Routledge Handbook of Francophone Africa

The Routledge Handbook of Francophone Africa brings together a multidisciplinary team of international experts to reflect on the history politics societies and cultures of French-speaking parts of Africa. Consisting of approximately 35% of Africa’s territory Francophone Africa is a shifting concept with its roots in French and Belgian colonial rule. This handbook develops and problematizes the term with thematic sections covering: Colonial and post-colonial ties between France and sub-Saharan Africa Belgium Belgian colonialism and Africa The Maghreb African Francophones in France Francophone African literature and film ‘Francophone’ and ‘Anglophone’ Africa Beyond national boundaries and ‘colonial partners’ The chapters demonstrate the evolution of Francophone Africa into a multi-dimensional construct with both a material and an imagined reality. Materially it defines a regional territorial space that coexists with other conceptualisations of African space and borders. Conceptually Francophone Africa constitutes a shared linguistic and cultural space within which collective memories are shared not least through their connection to the French imperial imagination. Overall the Handbook demonstrates that as global power structures and relations evolve African agency is increasingly assertive in shaping French-African relations. Bringing this important debate together into a single volume this Handbook will be an essential resource for students and scholars interested in Francophone Africa.

GBP 205.00
1

Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

This book provides an overview of the world market of therapeutic enzymes and enzyme inhibitors rare diseases orphan drugs the costs of drug development and therapies and enzymes in downstream processing of pharmaceuticals. It discusses carbonic anhydrase inhibitors and their multiple drug interactions carboxylesterase inhibitors for pharmaceutical applications employment of inhibitors for the treatment of neurodegenerative diseases use of engineered proteins bioactive peptides and fibrinolytic enzymes for thrombolytic therapy and enzymes important for the design and development of new drugs/drug metabolites such as aldehyde oxidases and cytochrome P450 enzymes and the role the latter play in vascular biology and pathophysiology. The treatment of cancer is explored in connection with enzymatic amino acid deprivation therapies and new drugs that act as chemical degraders of oncogenic proteins. The book also introduces the resistance mechanisms of cancer. Furthermore it provides an insight into the relationship between pathological conditions of cardiovascular disease and oxidative stress. The text also focuses on the potential use of nanoparticles as carriers for enzymes with medical relevance computer-aided drug design for the identification of multi-target directed ligands and the development of improved therapeutics through a glycan-“designer” approach. It concludes with an introduction to the chemoenzymatic synthesis of drugs. | Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

GBP 193.00
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The Routledge Companion to Literature and Social Justice

Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

The EURO-C conference series (Split 1984 Zell am See 1990 Innsbruck 1994 Badgastein 1998 St. Johann im Pongau 2003 Mayrhofen 2006 Schladming 2010 St. Anton am Arlberg 2014 and Bad Hofgastein 2018) brings together researchers and practising engineers concerned with theoretical algorithmic and validation aspects associated with computational simulations of concrete and concrete structures. Computational Modelling of Concrete Structures reviews and discusses research advancements and the applicability and robustness of methods and models for reliable analysis of complex concrete reinforced concrete and pre-stressed concrete structures in engineering practice. The contributions cover both computational mechanics and computational modelling aspects of the analysis and design of concrete and concrete structures: Multi-scale cement and concrete research: experiments and modelling Aging concrete: from very early ages to decades-long durability Advances in material modelling of plain concrete Analysis of reinforced concrete structures Steel-concrete interaction fibre-reinforced concrete and masonry Dynamic behaviour: from seismic retrofit to impact simulation Computational Modelling of Concrete Structures is of special interest to academics and researchers in computational concrete mechanics as well as industry experts in complex nonlinear simulations of concrete structures. | Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

GBP 290.00
1

Multiphase Particulate Systems in Turbulent Flows Fluid-Liquid and Solid-Liquid Dispersions

Multiphase Particulate Systems in Turbulent Flows Fluid-Liquid and Solid-Liquid Dispersions

Multiphase Particulate Systems in Turbulent Flows: Fluid-Liquid and Solid-Liquid Dispersions provides methods necessary to analyze complex particulate systems and related phenomena including physical chemical and mathematical description of fundamental processes influencing crystal size and shape suspension rheology interfacial area of drops and bubbles in extractors and bubble columns. Examples of mathematical model formulation for different processes taking place in such systems is shown. Discussing connections between turbulent mixing mechanisms and precipitation it discusses influence of fine-scale structure of turbulence including its intermittent character on breakage of drops bubbles cells plant cell aggregates. An important aspect of the mathematical modeling presented in the book is multi-fractal taking into account the influence of internal intermittency on different phenomena. Key Features Provides detailed descriptions of dispersion processes in turbulent flow interactions between dispersed entities and continuous phase in a single volume Includes simulation models and validation experiments for liquid-liquid gas-liquid and solid-liquid dispersions in turbulent flows Helps reader learn formulation of mathematical models of breakage or aggregation processes using multifractal theory Explains how to solve different forms of population balance equations Presents a combination of theoretical and engineering approaches to particulate systems along with discussion of related diversity with exercises and case studies | Multiphase Particulate Systems in Turbulent Flows Fluid-Liquid and Solid-Liquid Dispersions

GBP 200.00
1

Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

For decades biology has focused on decoding cellular processes one gene at a time but many of the most pressing biological questions as well as diseases such as cancer and heart disease are related to complex systems involving the interaction of hundreds or even thousands of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book‘s second half where much more complicated network models are addressed including transcriptional signaling metabolic and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates medical students and biologists new to mathematical modeling) while still having much to offer experienced modelers-whether their interests are microbes organs whole organisms diseases synthetic biology or just about any field that investigates living systems. | Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

GBP 180.00
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