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Foods Nutrition and Sports Performance An international Scientific Consensus organized by Mars Incorporated with International Olympic Comm

Foods Nutrition and Sports Performance An international Scientific Consensus organized by Mars Incorporated with International Olympic Comm

This book includes all the papers presented at the meeting revised to take account of all the points made during discussions and the Consensus Statement itself. The topics covered include recommendations for optimum carbohydrate protein fat total energy fluid and electrolyte and vitamin mineral intakes to maximise sports performance. | Foods Nutrition and Sports Performance An international Scientific Consensus organized by Mars Incorporated with International Olympic Comm

GBP 180.00
1

Pharmaceutical Biocatalysis Drugs Genetic Diseases and Epigenetics

Pharmaceutical Biocatalysis Drugs Genetic Diseases and Epigenetics

Volume 7 of the Jenny Stanford Series on Biocatalysis deals with several different aspects of pharmaceuticals which include not only various applications of drugs and their metabolism but also natural resources for active pharmaceutical ingredients as well as the removal of pharmaceutical pollution. In detail novel approaches for developing microbial fermentation processes to produce vitamin B6 using microorganisms are described together with novel routes for vitamin B6 biosynthesis. The other topics discussed are new approaches for producing the successful anticancer drug Taxol from naturally occurring precursors molecular farming through plant engineering as a cost-effective means to produce therapeutic and prophylactic proteins and successful screening of potent microorganisms producing L-asparaginase for various chemotherapeutic applications. Furthermore microbial biotransformations in the production and degradation of fluorinated pharmaceuticals are described. The other chapters inform the reader about the biotransformation of xenobiotics/drugs in living systems the degradation of pharmaceuticals by white-rot fungi and their ligninolytic enzymes and the removal of pharmaceutical pollution from municipal sewage using laccase. | Pharmaceutical Biocatalysis Drugs Genetic Diseases and Epigenetics

GBP 193.00
1

The Chemistry and Metabolism of 4' - Deoxypyridoxine

The Chemistry and Metabolism of 4' - Deoxypyridoxine

This review organizes the existing literature on deoxypyridoxine in order to provide additional insights for developing further work. By providing a thorough analysis of previous work with deoxypyridoxine it can be used more effectively as a tool for examining various metabolic pathways and explored further for its potential clinical use in cancer therapy immunosuppression or other areas. The book also stimulate some new insights into action of vitamin B6 itself. | The Chemistry and Metabolism of 4' - Deoxypyridoxine

GBP 180.00
1

Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

This volume of Pharmaceutical Biocatalysis starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types; human DOPA decarboxylase related to Parkinson's disease and aromatic amino acid decarboxylase deficiency; and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. An additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors targeting receptor tyrosine kinases in cancer β-Lactams and related compounds as antibacterials non-vitamin K oral anticoagulants for the treatment of thromboembolic diseases and the molecular mechanisms for statin pleiotropy and its clinical relevance in cardiovascular diseases. The last chapter is a review of lysosomal storage disorders with an overview of approved drugs for treating these disorders by enzyme replacement therapy. | Pharmaceutical Biocatalysis Important Enzymes Novel Targets and Therapies

GBP 193.00
1

Vitamins and Minerals in the Prevention and Treatment of Cancer

Vitamins and Minerals in the Prevention and Treatment of Cancer

This book provides researchers and practitioners with a unique collection of current research on the role of vitamins and micronutrients in cancer prevention and treatment. New theories are discussed including a hypothesis that dietary factors may protect against genetically predisposed cancers. Mechanisms by which different vitamins and minerals appear to inhibit carcinogenesis or cell transformation are described including vitamins A C E and selenium protection against oxidative stress by induction of enzymes as catalase and dismutase or inteference with free radical mechanisms; organosulfur compound inhibition of P450 activation enzymes or enhancement of detoxification enzymes; metal ion effects in the modulation of gene expression by site-specific binding of Zn-finger loop domains; B-carotene metabolite up-regulation of gap junctional communication between cells; and vitamin D3 elimination of amplified oncogenes or drug resistant genes. The book also reviews literature implicating a possible relationship between potassium and the control of cancer. Other information presented includes a discussion of contemporary technologies and data associating lipotrope deficiencies with alterations in xenobiotic metabolism nucleic acid methylation purine and pyrimidine synthesis signal transduction and chromosome anomalies. | Vitamins and Minerals in the Prevention and Treatment of Cancer

GBP 205.00
1