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Protein Purification

Protein Purification

This second edition of Protein Purification provides a guide to the major chromatographic techniques including non-affinity absorption techniques affinity procedures non-absorption techniques and methods for monitoring protein purity. The new edition of the book has been organized to encourage incremental learning about the topic starting with the properties of water progressing through the characteristics of amino acids and proteins which relate to the purification process. There is an overview of protein strategy and equipment followed by discussions and examples of each technique and their applications. The basic theory and simple explanations given in Protein Purification make it an ideal handbook for final year undergraduates and postgraduates who are conducting research projects. It will also be a useful guide to more experienced researchers who need a good overview of the techniques and products used in protein purification. Key Features * Guide to the major techniques used in protein purification * Includes flowcharts to help the reader slect the best purification strategy * Contains step-by-step protocols that guide the reader through each technique and its use * Includes exercises and solutions

GBP 66.99
1

The Fluorescent Protein Revolution

The Fluorescent Protein Revolution

Advances in fluorescent proteins live-cell imaging and superresolution instrumentation have ushered in a new era of investigations in cell biology medicine and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins The Fluorescent Protein Revolution explores the history properties and applications of these important probes. The book first traces the history of fluorescent proteins and the revolution they enabled in cellular imaging. It then discusses fluorescent proteins with novel photophysical properties. The book also covers several cutting-edge imaging applications. These include superresolution microscopy of cellular fine structures FRET microscopy to visualize protein interactions and cell-signaling activities inside living cells photobleaching and photoactivation techniques to visualize protein behaviors techniques that exploit plant and algal photoreceptors to enable light-regulated control of enzymatic activities and the noninvasive imaging of tumor–host interactions in living animals. In color throughout this book presents the fundamental principles and latest advances in the field including the associated development of imaging techniques that exploit fluorescent proteins. It is accessible to a broad audience from optical imaging experts to novices needing an introduction to the field.

GBP 59.99
1

Peptide and Protein Drug Analysis

Peptide and Protein Drug Analysis

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad comprehensive overview of peptides and proteins as mediators of cell movement proliferation differentiation and communication. Written by more than 50 leading international authorities Peptides and Protein Drug Analysisdiscusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic capillary electrophoretic gel electrophoretic and isoelectric focusing methods highlights drug design elements derived from protein folding bioinformatics and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry protein sequence and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet fluorescence Fourier transform infrared and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light X-ray and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables equations and illustrations Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical organic and pharmaceutical chemis

GBP 59.99
1

Computational Approaches to Protein Dynamics From Quantum to Coarse-Grained Methods

Computational Approaches to Protein Dynamics From Quantum to Coarse-Grained Methods

The Latest Developments on the Role of Dynamics in Protein Functions Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods presents modern biomolecular computational techniques that address protein flexibility/dynamics at all levels of theory. An international contingent of leading researchers in chemistry physics and biology show how these advanced methods provide insights into dynamic aspects of biochemical processes. A particular focus is on intrinsically disordered proteins (IDPs) which lack a well-defined three-dimensional structure and function as dynamic ensembles. The book covers a wide spectrum of dynamics from electronic structure-based to coarse-grained techniques via multiscaling at different levels. After an introduction to dynamics and historical overview of basic methodologies the book addresses the following issues: Is there a quantitative relationship between enzymatic catalysis and protein dynamics? Which are the functionally relevant motions of proteins? How can structural properties and partner recognition mechanisms of IDPs be simulated? How can we speed up molecular dynamics? How can we describe conformational ensembles by the synergistic effort of computations and experiments? While dynamics is now considered essential for interpreting protein action it is not yet an integral component in establishing structure–function relationships of proteins. Helping to reshape this classical view in biochemistry this groundbreaking book explores advances in computational methodology and contributes to the new ensemble way of studying proteins. | Computational Approaches to Protein Dynamics From Quantum to Coarse-Grained Methods

GBP 69.99
1

Phage Display In Biotechnology and Drug Discovery

Phage Display In Biotechnology and Drug Discovery

Phage Display in Biotechnology and Drug Discovery Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition the book discusses current theories principles and methods in the field and demonstrates applications for peptide phage display protein phage display and the development of novel antibodies. The book provides readers with an overview of the amazing breadth of the impact that phage display technology has had on the study of proteins in general as well as the development of proteins. It will be a valuable resource for those interested in using phage display and recombinant antibodies in basic research and drug discovery. Key Features: Describes the basic principles of phage display and the methods and systems that have been developed for key applications Outlines applications for peptide phage display in the development of vaccines and high- throughput screens as well as the exploration of protein–protein interactions and enzyme substrate characteristics Details the use of phage display in the engineering of protein stability the identification and mapping of protein–protein interactions and the development of catalysts Provides broad coverage of the impact of phage display technology on the development of protein therapeutics Presents expert opinions on future challenges in the field

GBP 69.99
1

Introduction to Computational Proteomics

Introduction to Computational Proteomics

Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis classification and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entities from protein families to interactions cellular pathways and gene networks. The first part of the book presents methods for identifying the building blocks of the protein space such as motifs and domains. It also describes algorithms for assessing similarity between proteins based on sequence and structure analysis as well as mathematical models such as hidden Markov models and support vector machines that are used to represent protein families and classify new instances. The second part covers methods that investigate higher order structure in the protein space through the application of unsupervised learning algorithms such as clustering and embedding. The book also explores the broader context of proteins. It discusses methods for analyzing gene expression data predicting protein-protein interactions elucidating cellular pathways and reconstructing gene networks. This book provides a coherent and thorough introduction to proteome analysis. It offers rigorous formal descriptions along with detailed algorithmic solutions and models. Each chapter includes problem sets from courses taught by the author at Cornell University and the Technion. Software downloads data sets and other material are available at biozon. org

GBP 59.99
1

Nanotechnology in Drug Delivery Fundamentals Design and Applications

Nanotechnology in Drug Delivery Fundamentals Design and Applications

This important new book provides the fundamental understanding of the peptide and protein drug delivery systems with a special focus on their nanotechnology applications. Addressing an increasing interest in peptide and protein drug delivery systems in both academic and industrial circles worldwide this book fills the need for a comprehensive review and assessment of conventional and nonconventional routes of administration. | Nanotechnology in Drug Delivery Fundamentals Design and Applications

GBP 82.99
1

Knowledge Discovery in Proteomics

Knowledge Discovery in Proteomics

Multi-modal representations the lack of complete and consistent domain theories rapid evolution of domain knowledge high dimensionality and large amounts of missing information - these are challenges inherent in modern proteomics. As our understanding of protein structure and function becomes ever more complicated we have reached a point where the actual management of data is a major stumbling block to the interpretation of results from proteomic platforms to knowledge discovery. Knowledge Discovery in Proteomics presents timely authoritative discussions on some of the key issues in high-throughput proteomics exploring examples that represent some of the major challenges of knowledge discovery in the field. The authors focus on five specific domains:Mass spectrometry-based protein analysisProtein-protein interaction network analysisSystematic high-throughput protein crystallizationSystematic integrated analysis of multiple data repositoriesSystems biologyIn each area the authors describe the challenges created by the type of data produced and present potential solutions to the problem of data mining within the domain. They take a systems approach covering individual data and integrating its computational aspects from data preprocessing storage and access to analysis visualization and interpretation. With clear exposition practical examples and rich illustrations this book presents an outstanding overview of this emerging field and builds the background needed for the fruitful exchange of ideas between computational and biological scientists.

GBP 59.99
1

Introduction to Proteins Structure Function and Motion Second Edition

Introduction to Proteins Structure Function and Motion Second Edition

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure function and motion of proteins for students faculty and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications including medical disorders drugs toxins chemical warfare and animal behavior. Each chapter includes a Summary Exercises and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis describing enzyme biochemistry classification kinetics thermodynamics mechanisms and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins including fully accessible internet-based resources such as databases and algorithms Animations of protein dynamics and conformational changes accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding stability and interactions A comprehensive view of membrane proteins with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins providing a complete realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary Exercies and References Approximately 300 color images Downloadable solutions manual available at www. crcpress. com For more information including all presentations tables animations and exercises as well as a complete teaching course on proteins' structure and function please visit the author's website. Praise for the first edition This book captures in a very accessible way a growing body of literature on the structure function and motion of proteins. This is a superb publication that would be very useful to undergraduates graduate students postdoctoral researchers and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships. David Sheehan ChemBioChem 2011 Introduction to Proteins is an excellent state-of-the-art choice for students faculty or researchers needing a monograph on protein structure. This is an immensely informative thoroughly researched up-to-date text with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure and a valuable addition to the libraries of professionals interested in this centrally important field. Eric Martz Biochemistry and Molecular Biology Education 2012 | Introduction to Proteins Structure Function and Motion Second Edition

GBP 84.99
1

Plant Biotechnology Volume 1 Principles Techniques and Applications

Plant Biotechnology Volume 1 Principles Techniques and Applications

This book first of this new two-volume set provides an informative tour of the basics of biotechnology to recent advances in biotechnology. Knowledge of new and fresh approaches is a prerequisite to solving plant biological problems and to this end the editors have brought together a group of contributors who address the most recent techniques and their applications in plant biotechnology. The chapters discuss some recent techniques such as TILLING (Targeting Induced Local Lesions In Genomes) advances in molecular techniques to study diversity protein purification and methods and analysis in protein-protein interaction detection. The volume also covers molecular markers and QTL mapping including four chapters that deal with different molecular markers development of mapping populations and association mapping for dissecting the genetic basis of complex traits in plants in sufficient detail. The knowledge of biotechnology techniques and their applications will be valuable for researchers and scientists as well as for the many students engaged in plant biotechnology studies. | Plant Biotechnology Volume 1 Principles Techniques and Applications

GBP 82.99
1

Nutritional Guidelines for Athletic Performance The Training Table

Nutritional Guidelines for Athletic Performance The Training Table

Knowing the basic nutrition requirements and combining them with proper training are the two most important factors for athletes to achieve peak performance levels. Nutritional Guidelines for Athletic Performance: The Training Table addresses these needs on a comprehensive basis from a training table perspective. Offering practical guidelines for practitioners and athletes the book focuses on the key macronutrients that fuel daily metabolism and exercise training and explores differing needs for various athletes and their individual goals. Topics discussed include:General principles and physiology of caloric intake for all major macronutrients and how this pertains to both active and sedentary individualsEnergy demands and nutritional requirements for strength-power athletes and elite competitors in endurance sports Protein carbohydrate fat vitamin and mineral needs of athletesThe importance of optimal fluid and hydration during exerciseHow to determine body weight for a desired body fat percentage recommended calorie consumption dietary suggestions and useful meal planning tools for a wide variety of caloric needsThe difference between energy intake and energy expenditure and how athletes can eat to build muscle lose fat and optimize performanceScientific strategies on how to time exercise and food intake to more effectively replenish glycogen increase protein synthesis and blunt protein degradationHow the physiological changes that accompany aging change nutrient needs and guidelines for older athletes on maximizing performance and maintaining healthStructuring a diet containing appropriate amounts of macronutrients (protein carbohydrates and fat) and micronutrients (vitamins and minerals) can be a daunting task. This text adequately addresses how athletes can do so in an effe | Nutritional Guidelines for Athletic Performance The Training Table

GBP 59.99
1

Informatics In Proteomics

Informatics In Proteomics

The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists biostatisticians and biologists to develop tools for storing retrieving visualizing and analyzing genomic data. Informatics in Proteomics examines the ongoing advances in the application of bioinformatics to proteomics research and analysis. Through computer simulations scientists can determine more about how diseases affect cells predict how various drug interventions would work and ultimately use proteins as therapeutic targets. This book first addresses the infrastructure needed for public protein databases. It discusses information management systems and user interfaces for storage retrieval and visualization of the data as well as issues surrounding data standardization and integration of protein sequences recorded in the last two decades. The authors subsequently examine the application of statistical and bioinformatic tools to data analysis data presentation and data mining. They discuss the implementation of algorithms statistical methods and computer applications that facilitate pattern recognition and biomarker discovery by integrating data from multiple sources. This book offers a well-rounded resource of informatic approaches to data storage retrieval and protein analysis as well as application-specific bioinformatic tools that can be used in disease detection diagnosis and treatment. Informatics in Proteomics captures the current state-of-the-art and provides a valuable foundation for future directions.

GBP 59.99
1

Amino Acids Biochemistry and Nutrition

Amino Acids Biochemistry and Nutrition

Following its predecessor the second edition of Amino Acids: Biochemistry and Nutrition presents exhaustive coverage of amino acids in the nutrition metabolism and health of humans and other animals. Substantially revised expanded and updated to reflect scientific advances this book introduces the basic principles of amino acid biochemistry and nutrition while highlighting the current knowledge of the field and its future possibilities. The book begins with the basic chemical concepts of amnio acids peptides and proteins and their digestion and absorption. Subsequent chapters cover cell- tissue- and species-specific synthesis and catabolism of amino acids and related bioactive metabolites and the use of isotopes to study amino acids metabolism in cells and the body. The book details protein turnover physiological functions of amino acids as well as both the regulation and inborn errors of amino acid metabolism. The book concludes with a presentation on human and animal dietary requirements of amino acids and evaluates dietary protein quality. Features: Encompasses a comprehensive coverage of basic to applied concepts in amino acid metabolism in humans and other animals. Highlights important roles of dietary amino acids and protein intake in growth physical performance and health including sarcopenia mitigation and immunity. Discusses concerns over the excess intakes of amino acids or protein in the development of diseases including cardiovascular disorders diabetes and cancers as well as bone integrity Each chapter contains select references to provide comprehensive reviews and original experimental data on the topics discussed. Each chapter is backed by original experimental data on various topics discussed and contains select references to aid the reader further in research. Written by Distinguished Professor of Animal Nutrition Guoyao Wu Ph. D. this book is an authoritative reference for students and researchers in both biomedicine and agriculture. | Amino Acids Biochemistry and Nutrition

GBP 74.99
1

Receptor - Based Drug Design

Receptor - Based Drug Design

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels this detailed single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design. Explains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process! Demonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions Receptor-Based Drug Designintroduces novel computer-assisted strategies for the design of new agonists antagonists and inverse agonists for G-protein-coupled receptors shows how to assess agonist concentration-effect curve data discusses radioligand binding assays presents new in vitro multiarray assays for G-protein-coupled receptors explains the use of individual second messenger signaling responses in analyzing drug-receptor interactions examines the role of electrophysiology in finding new drugs and drug targets describes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment outlines the rationale for using angiotensin receptor antagonists and more! Written by over 25 international authorities and containing nearly 1200 bibliographic citations Receptor-Based Drug Design is a practical resource for pharmacologists pharmacists and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines. | Receptor - Based Drug Design

GBP 59.99
1

Behavioral Neuroendocrinology

Behavioral Neuroendocrinology

Inspired by Carlos Beyer’s 50 years of pioneering research and influence on his students and colleagues Behavioral Neuroendocrinology builds upon Beyer’s fundamental discoveries and concepts as well as their widespread implications. It presents original research and reviews on mechanisms — genomic and non-genomic — of steroid and protein hormone action; the role of steroid metabolism especially aromatization protein phosphorylation and neurotransmitter action in mediating reproductive behavior and sexual differentiation; and brain and spinal cord mechanisms in sexual behavior and analgesia. This book presents a rich diversity of topics — lactation maternal behavior pheromone action chronobiology allodynia angiogenesis prostate physiology sexual motivation and specific brain systems including vomeronasal system cerebellum preoptic area hypothalamus and spinal cord. This book brings together in one source an international family of researchers whose work has evolved in diverse but related ways from a seminal set of discoveries and concepts in behavioral neuroendocrinology.

GBP 44.99
1

Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology biochemistry bioinformatics and pharmacology as well as medical students. The text is organized by three key topics central to signal transduction: the protein network its energy supply and its evolution. It covers all important aspects of cell signaling ranging from prokaryotic signal transduction to neuronal signaling and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes as well as content on new developments in systems biology epigenetics redox signaling and small non-coding RNA signaling. | Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

GBP 66.99
1

Cell Membrane Nanodomains From Biochemistry to Nanoscopy

Cell Membrane Nanodomains From Biochemistry to Nanoscopy

Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells new fluorescent proteins novel Laurdan analyses and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior the book concludes with a discussion of technologies that are enabling the visualization of lipids proteins and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field including new methods and data analysis tools that exclusively pertain to these techniques. This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools. | Cell Membrane Nanodomains From Biochemistry to Nanoscopy

GBP 44.99
1

Fermentation Microbiology and Biotechnology Fourth Edition

Fermentation Microbiology and Biotechnology Fourth Edition

Fermentation Microbiology and Biotechnology 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area. Key FeaturesCovers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering. Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies. Presents the contributions of eminent international academics and industrial experts. Offers new chapters addressing:The prospects and the role of bio-fuels refineries Control of metabolic efflux to product formation in microbial-cell factories andImproving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel. | Fermentation Microbiology and Biotechnology Fourth Edition

GBP 46.99
1

Silkworm Biofactory Silk to Biology

Silkworm Biofactory Silk to Biology

While silk derived from silkworm has been of economic importance for centuries more recently silkworm has been found to have utility in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins which require post-translational modifications. In 1985 Dr. Susumu Maeda demonstrated that silkworm larvae could produce a functional human-interferon. Since then various techniques have been developed to express recombinant proteins in silkworm. With the development of the Bombyx mori nucleopolyhedrovirus (BmNPV) bacmid system which is capable of replicating in both Escherichia coli and Bombyx mori derived cell lines or silkworm silkworm larvae or pupae have been used for the expression system for recombinant protein production. This method has the advantage of a bacmid in that it can be easily prepared for sufficient bacmid DNA for subsequent expression in silkworm. It is potentially a big breakthrough in production of recombinant eukaryotic proteins and viruses which will be a powerful tool in a new proteome era. This volume contributes to the advancement of our knowledge in the subject for example gene expression systems and silkworm research and focuses on silkworm biofactories for the recombinant protein production and commercial applications of proteins. | Silkworm Biofactory Silk to Biology

GBP 44.99
1

Process Scale Bioseparations for the Biopharmaceutical Industry

Process Scale Bioseparations for the Biopharmaceutical Industry

The biopharmaceutical industry has become an increasingly important player in the global economy and the success of these products depends on the development and implementation of cost-effective robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceutical developers. Process Scale Bioseparations for the Biopharmaceutical Industry brings together scientific principles empirical approaches and practical considerations for designing industrial downstream bioprocesses for various classes of biomolecules. Using clear language along with numerous case studies examples tables flow charts and schematics the book presents perspectives from experienced professionals involved in purification processes and industrial downstream unit operations. The authors provide useful experimental design strategies and guidelines for developing application-specific process scale bioseparations. Chapter topics include harvest by centrifugation and filtration expanded bed chromatography protein refolding modes of preparative chromatography methodologies for resin screening membrane chromatography protein crystallization viral filtration ultrafiltration/diafiltration implementing post-approval downstream process changes for an antibody product and future trends. Ideal for both new and experienced scientists in the biopharmaceutical industry and students Process Scale Bioseparations for the Biopharmaceutical Industry is a comprehensive resource for all topics relevant to industrial process development.

GBP 44.99
1

Amyloid and Amyloidosis

Amyloid and Amyloidosis

This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins protein folding disorders and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders diagnosis and treatments including organ transplants and drug therapies; results from extensive clinical studies; and epidemiology. This is a valuable resource for clinicians who care for patients with systemic and localized forms of amyloidosis and for researchers in biochemistry neurobiology and cell biology. | Amyloid and Amyloidosis

GBP 59.99
1

Computational Biochemistry and Biophysics

Computational Biochemistry and Biophysics

Covering theoretical methods and computational techniques in biomolecular research this book focuses on approaches for the treatment of macromolecules including proteins nucleic acids and bilayer membranes. It uses concepts in free energy calculations conformational analysis reaction rates and transition pathways to calculate and interpret biomolecular properties gleaned from computer-generated membrane simulations. It also demonstrates comparative protein structure modeling outlines computer-aided drug design discusses Bayesian statistics in molecular and structural biology and examines the RISM-SCF/MCSCF approach to chemical processes in solution. | Computational Biochemistry and Biophysics

GBP 59.99
1